General Cell Based Assays
Perkin Elmer US LLC UATR Sample Position Plate - 3 mm
The PerkinElmer Universal ATR (UATR) Accessory is ideal for the general IR analysis of solids and liquids. The UATR comes in a variety of crystal configurations as well as single/multiple reflections capabilities. It produces high quality spectra through the use of a pressure arm. The pressure arm force indicator ensures sample-to-sample and operator-to-operator reproducibility. The accessory is recognized when it is placed in the spectrometer's sample compartment, the optics are automatically optimized, and the system is ready to be used without additional alignment. This UATR is compatible with the Spectrum One/100/400/65 and Spectrum 3/Frontier spectrometers.
Cayman Chemical NFAT Activation Inhibitor III, Purity: ≥98%, CAS: 3519-82-2, 25 mg
A cell-permeant inhibitor of NFAT signaling; binds calcineurin (Kd = 0.8 µM), preventing it from dephosphorylating NFAT
Eurofins Discoverx PathHunter Human KDR Kinase Activity Cell-Based Assay Kit (U2OS)
The PathHunter Human KDR Stable Cell Line Kinase Activity Assay (U2OS) measures KDR receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
ACROBiosystems Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human, 500 tests
Human Fc gamma RIIA / CD32a (R167) binding Kit (TR-FRET) is expressed from Human
Abcam LDL-DyLightTM 550.
LDL-DyLightTM 550.
The product is subject to the following: Abcam Restricted Use Statement
ACROBiosystems Human Fc gamma RIIA / CD32a (H167) binding Kit (TR-FRET) is expressed from Human, 10000 tests
Human Fc gamma RIIA / CD32a (H167) binding Kit (TR-FRET) is expressed from Human
Abcam Glucose Uptake Assay Kit (Colorimetric)
Glucose Uptake Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter OSMRb/IL31R Bioassay Kit, 10-Plate. (93-1002Y3-00084)
The PathHunter OSMRb/IL31R Dimerization Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. IL-31) induced dimerization of OSMRb/IL31R receptors. This product uses EFC technology. The cell line included overexpresses OSMRb target protein fused to PK alongside IL31RA target protein fused to EA. Upon ligand-induced dimerization of OSMRb/IL31R, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter eXpress GPR137 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0361E2ACP1M)
The PathHunter GPR137 (TM7SF1) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR137 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR137 and EA-tagged β-Arrestin-2. Activation of GPR137 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Adipolysis Assay Kit.
Adipolysis Assay Kit.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx HitHunter cAMP Assay for Biologics, 1,000/4,000 dp (96-well/384-well). (90-0075LM10)
This detection kit is a robust, sensitive and easy-to-use assay to determine GPCR activity through detection of intracellular cAMP levels. The HitHunter cAMP assay is intended for use with cells expressing Gαs- or GαI-coupled GPCRs. This product uses EFC technology, and contains ED-tagged cAMP, anti-cAMP antibody, and pure EA. Upon application to a cell which contains endogenous, untagged cAMP, the anti-cAMP antibody will be sequestered by binding to this untagged cAMP, allowing for EFC between the tagged cAMP and soluble EA. This will produce a proportional level of chemiluminescent signal. This kit format is intended for Biologic drugs with a protocol optimized for use in a 96-well plate. This kit may be used with Eurofins DiscoverX cAMP cell lines as well as cell lines from other sources. This detection kit contains reagents for assaying 10 plates (96-well). For detailed product information, visit www.discoverx.com/products-applications/biochemical-assays.
Eurofins Discoverx PathHunter eXpress SSTR3 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0244E2CP0M)
The PathHunter SSTR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged SSTR3 and EA-tagged β-Arrestin-2. Activation of SSTR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GRPR U2OS β-Arrestin GPCR Assay, 10-Plate Kit. (93-0229E3CP5L)
The PathHunter GRPR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. gastrin-releasing peptide) based activation of GRPR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GRPR and EA-tagged β-Arrestin-2. Activation of GRPR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress OSMR/IL6ST Dimerization Assay, 10pl Kit. (93-1056E3CP5L)
The PathHunter OSMR/IL6ST Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. oncostatin M) induced dimerization of OSMR/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside OSMR target protein fused to EA. Upon ligand-induced dimerization of OSMR/IL6ST, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress IL17RD/TNFR2 Dimerization Assay, 2pl Kit. (93-1068E3CP5M)
The PathHunter IL17RD/TNFR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. TNFα) induced dimerization of IL17RD/TNFR2 receptors. This product uses EFC technology. The cell line included overexpresses IL17RD target protein fused to PK alongside TNFR2 target protein fused to EA. Upon ligand-induced dimerization of IL17RD/TNFR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.